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LAST NEWS
2010-09-03
Conn. cigarette tax hike raises more than expected
Connecticut's $1-a-pack tax hike on cigarettes has brought in $5 million more in revenue than expected since the increase went into place last October.
http://www.timesunion.com/
2010-05-15
Feds arrest ex-Orland shopkeep
Federal authorities have extradited a onetime Orland Park tobacco shop owner from Germany who is under investigation for allegedly funneling money to a Lebanese organization that the United States has designated as “hostile,” the Chicago Sun-Times is reporting.
http://www.southtownstar.com/
2010-04-09
Majority Will Vote For Smoking Ban
It passed the legislature and was signed by the governor. South Dakota's smoking ban was set to go into effect last July.
http://www.keloland.com/
2010-03-22
Tobacco farmers trying to save water-soaked crop
While some Wisconsin tobacco producers should have a good crop this year, the area's extremely wet August is expected to make for a down year overall.
http://www.courierlifenews.com/
2010-03-12
Reynolds Loses Cigarette Case
A Vermont state judge ruled Wednesday that R.J. Reynolds Tobacco Co. made false and misleading marketing claims last decade to sell its Eclipse cigarette brand, in a case that highlighted a fierce debate over so-called reduced-harm cigarettes.
http://online.wsj.com/


Other News

Tobacco News


Brain chemicals can thwart desire to smoke cigarettes
Categories:
· Health/Science
Source:Health Behavior Information Transfer,2002-09-03
Giving smokers medication to mimic an increase in their brain's level of a substance called dopamine could help squelch their desire for cigarettes, according to a new study.
Researchers examined 20 heavy smokers who were given two drugs that either increased or decreased the brain's level of dopamine, a neurotransmitter that affects motor function. Dopamine, a chemical in the central nervous system, is believed to affect emotion, and research on animals has shown that nicotine causes a release of dopamine in brain areas that are associated with feelings of pleasure.

Test subjects smoked less when given a drug that mimics the effects of dopamine in the brain than they did when given a second drug that impedes dopamine's effects. When the subjects were given the dopamine-mimicking drug, their desire to smoke dropped, but when the same smokers were given the dopamine-impeding drug, they took longer and more frequent puffs of smoke.

"Overall, these results imply that smoking behavior can be manipulated within the same subjects in opposite directions by alternately stimulating and blocking dopamine, which strongly suggests the importance of dopamine in reinforcement from cigarette smoking," notes lead researcher Nicholas H. Caskey, Ph.D., of the Veterans Affairs Greater Los Angeles Healthcare System and the Neuropsychiatric Institute at UCLA's David Geffen School of Medicines.

The dopamine-mimicking drug used by the researchers, bromocriptine, is used to treat menstrual problems, some tumors and Parkinson's disease. Administration of the drug over a five-hour period caused the subjects to smoke fewer cigarettes and take fewer puffs and have a shorter total puffing time compared with their smoking behavior when given the dopamine-impeding drug.

Prior to this study, very few studies examined the effects of nicotine on dopamine levels in humans. Dopamine is also believed to play a role in regulating the addictive effects of other stimulant drugs such as cocaine and amphetamines.

Researchers monitored the level of nausea in each subject to ensure that smoking levels did not change because of side effects of the drugs. "The … results suggest that nausea played some role in the … response in smoking behavior to the two drugs, but also clearly indicate that there is a substantial drug effect independent of nausea," they write.

The study, which is published in the September issue of Nicotine & Tobacco Research, was funded by a grant from the National Institutes of Health.
 

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